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Your current location:Home » Product supply » HMG Gonadotropin Injection Human Menopausal Urine Anti-aging Mass Building Supplements
HMG Gonadotropin Injection Human Menopausal Urine Anti-aging Mass Building Supplements
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Product: Views:8HMG Gonadotropin Injection Human Menopausal Urine Anti-aging Mass Building Supplements 
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Last updated: 2017-01-16 06:12
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HMG Gonadotropin Injection from Human Menopausal Urine,Anti-aging Mass Building Supplements
 
Description:

Human Menopausal Gonadotropins are protein hormones secreted by gonadotrope cells of the pituitary gland of vertebrates.Gonadotropin is sometimes abbreviated Gn. The British spelling isgonadotrophin.

hMG is produced from a sterile preparation of placental glucoprotein urine of post-menopausal women. The HMG is purified by proprietary chromatographic techniques.

Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.

 

Types:

The two principal gonadotropins are luteinizing hormone (LH) and follicle stimulating hormone (FSH). Both hormones consist of two peptide chains, an alpha chain and a beta chain, linked by Hydrogen bonds and van der Waals forces. LH and FSH share nearly identical alpha chains, while the beta chain provides specificity for receptor interactions.

A third human gonadotropin is human chorionic gonadotropin (hCG), produced by the placenta during pregnancy.

 

Mechanism:

Gonadotropin receptors are embedded in the surface of the target cell membranes and coupled to the G-protein system. Signals triggered by binding to the receptor are relayed within the cells by the cyclic AMP second messenger system.

Gonadotropins are released under the control of gonadotropin-releasing hormone (GnRH) from the arcuate nucleus and preoptic area of the hypothalamus. The gonads — testes and ovaries — are the primary target organs for LH and FSH. The gonadotropins affect multiple cell types and elicit multiple responses from the target organs. As a simplified generalization, LH stimulates the Leydig cells of the testes and the theca cells of the ovaries to produce testosterone (and indirectly estradiol), while FSH stimulates the spermatogenic tissue of the testes and the granulosa cells of ovarian follicles.

 

Diseases:

Gonadotropin deficiency due to pituitary disease results in hypogonadism, which can lead to infertility. Treatment include administered gonadotropins, which therefore work as fertility medication. Such can either be produced by extraction and purification from urine or it can be produced by recombinant DNA.

Failure or loss of the gonads usually results in elevated levels of LH and FSH in the blood.

 

Manny ramirez controversy:

Major League baseball player Manny Ramirez was suspended for 50 games on May 6, 2009, for allegedly failing a drug test which identified gonadotropin.

 

 

Formulation:

Lyophilized from a concentrated (1 mg/ml) solution in water containing no additives.

 

Solubility:

It is recommended to reconstitute the lyophilized hMG in sterile 18MO-cm H2O not less than 100 g/ml, which can then be further diluted to other aqueous solutions.

 

Stability:

Lyophilized hMG although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution hMG should be stored at 4 C between 2-7 days and for future use below -18 C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.

 

Purity:

Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Anion-exchange FPLC. (c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.

 

Storage:

should be stored desiccated below -18°C. Upon reconstitution HMG should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycle.

 


Competitive Advantage:

  • High quality and facoty price.
  • Professional
  • Fast shipment
  • Very good customer service.

 
 
Delivery and shipping:
1. We will ship the goods within 1 days after payment.
 
2. We will ship the goods by EMS or DHL. We will choose the best courier depend on different countries, and find the safest way to deliver the goods for you.
 
3. As usual you can get the goods with in 4-7 business days. If the goods were lost or not received for other reasons, well resend.
 
We have many regular customers worldwide, and hope to establish long-term cooperation with you.
For further informations please feel free to contact us, we’ll do our best to fulfill your request. Thanks.
 
 


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